Preterm birth is defined as delivery occurring before 37 weeks gestation.1 Infants born prematurely have increased risks of morbidity and mortality throughout life, especially during the first year. These risks increase as the gestational age at birth decreases.2 Additionally, there are significant racial and ethnic differences in preterm birth rates. In 2022, the rate of preterm birth among non-Hispanic black women was approximately 50% higher than that observed in non-Hispanic white women.1 The outcomes for these infants are also disparate–preterm birth (...) and low birth weight are the second-leading causes of infant mortality (deaths before 1 year of age). Notably, among preterm neonates, infants born to non-Hispanic black women have a mortality rate more than double that of infants born to non-Hispanic white mothers.3 Importantly, there is a small but significant group of neonates that can be classified as severely premature (those born <28 weeks). Infants born before 28 weeks have varied and uncertain outcomes. While this group accounts for only 0.4% of preterm births, it also accounts for 40% of deaths among preterm neonates.4 As noted by Romanis and Adkins, the advent of artificial amnion and placenta technology (AAPT) holds promise for its potential to address the physiologic complications and mortality risks of extreme prematurity by introducing amniotic substitutes that mimic in vivo placental oxygenation and substrate delivery. In contrast …. (shrink)

A dictionary definition of Bioethics is, 'the ethics, or moral principles and rules of conduct, of medical and biological research'. This book is an introductory text of just biological and not medical bioethics. It covers the ethics of experimentation, including genetic manipulation, in plants and animals; ethics and biodiversity, ethics and the environment. There is increasing interest in bioethics - both in academia and by the media and the general public. Awareness of bioethics is incorporated into Biological / Environmental Science (...) courses, plus the first dedicated modular courses on bioethics are starting up. * Includes case studies * Has questions for students * Chapters include environmental, animal, agricultural and reproductive ethics as well as a wide range of issues regarding genetic manipulation. (shrink)

The philosophical difficulties presented by self-deception are vexed and multifaceted. One such difficulty is what I call the ‘doxastic problem’ of self-deception. Solving the doxastic problem involves determining whether someone in a state of self-deception that ∼p both believes that p and believes that ∼p, simply holds one or the other belief, or, as I will argue, holds neither. This final option, which has been almost entirely overlooked to-date, is what I call ‘ nondoxasticism ’ about self-deception. In this article, (...) I present a negative case for nondoxasticism according to which, in the paradigm case of self-deception, there is no explanatory need to attribute the self-deceived person either their undesired belief that p, or their desired belief that ∼p. Folk psychology is replete with concepts other than belief, and if we bear this in mind, it becomes clear that the explanatory roles for which the self-deceived person's purported beliefs have traditionally been enlisted can be comfortably filled without recourse to belief. (shrink)

Provides comprehensive, yet concise coverage of the broad field of bioethics, dealing with the scientific, medical, social, religious, political and international concerns.

This article takes as its starting point the central place given to contradiction by Hermann Goldschmidt in his book Contradiction Set Free, and it compares his approach with that of the philosopher Vladimir Jankélévitch. At the same time as Goldschmidt, Jankélévitch also assigned a central role to contradiction in thought, so much so that he often referred to his own philosophical method as “paradoxology.” For him, as for Goldschmidt, paradox is the driving force behind thought that is always on the (...) move. This article presents the main features of Jankélévitch’s paradoxology and illustrates it with two themes: forgiveness and Jewish identity. By highlighting this proximity between Goldschmidt’s approach and that of Jankélévitch, I suggest that they are both part of a more general movement in continental philosophy in the second half of the twentieth century, one of whose main challenges was to rethink philosophical rationality in depth. (shrink)

William James famously tells us that there are two main goals for rational believers: believing truth and avoiding error. I argues that epistemic consequentialism—in particular its embodiment in epistemic utility theory—seems to be well positioned to explain how epistemic agents might permissibly weight these goals differently and adopt different credences as a result. After all, practical versions of consequentialism render it permissible for agents with different goals to act differently in the same situation. -/- Nevertheless, I argue that epistemic consequentialism (...) doesn’t allow for this kind of permissivism and goes on to argue that this reveals a deep disanalogy between decision theory and the formally similar epistemic utility theory. This raises the question whether epistemic utility theory is a genuinely consequentialist theory at all. (shrink)

A rich literature has discussed what it is to respond to a reason, e.g., to believe or act on the basis of some consideration or another. In comparison, what it would be to respond to a second-order reason has been underexplored. Yet formulating an account of this is vital for maintaining the existence of second-order reasons in both the practical and epistemic domains. And indeed, there are reasons to doubt this is possible. For example, responding to second-order reasons is meant (...) to be different from simply coming to believe or act for a more richly described first-order reason but it's not clear what this would look like. This paper introduces an account of the second-order basing relation which meets these concerns. It therefore both develops our picture of second-order reasons and helps to defend their existence. (shrink)

We all experience loneliness at some time in our lives and it often motivates people, consciously or otherwise, to enter treatment. Yet it is rarely explicitly addressed in psychoanalytic literature. Loneliness and Longing rectifies this oversight by thoroughly exploring this painful psychological state. In this book contributors address the inner sense of loneliness âe" that is feeling alone even in the company of others âe" by drawing on different aspects of loneliness and longing. Topics covered include: loneliness in the consulting (...) room the relationship between loneliness and love the effects of social networking and the internet how loneliness changes throughout the life-cycle healing the analystâe(tm)s loneliness. Loneliness and Longing draws on both theory and practice to discuss ways to help people to understand and cope with this important emotional state, encouraging them to make loneliness and longing less pervasive in their lives. This will be ideal reading for analysts, psychotherapists, and related practitioners facing the challenges of loneliness in their consulting rooms. (shrink)

According to a grand narrative that long ago ceased to be told, there was a seventeenth century Scientific Revolution, during which a few heroes conquered nature thanks to mathematics. This grand narrative began with the exhibition of quantitative laws that these heroes, Galileo and Newton for example, had disclosed: the law of falling bodies, according to which the speed of a falling body is proportional to the square of the time that has elapsed since the beginning of its fall; the (...) law of gravitation, according to which two bodies are attracted to one another in proportion to the sum of their masses and in inverse proportion to the square of the distance separating them -- according to his own preferences, each narrator added one or two quantitative laws of this kind. The essential feature was not so much the examples that were chosen, but, rather, the more or less explicit theses that accompanied them. First, mathematization would be taken as the criterion for distinguishing between a qualitative Aristotelian philosophy and the new quantitative physics. Secondly, mathematization was founded on the metaphysical conviction that the world was created pondere, numero et mensura, or that the ultimate components of natural things are triangles, circles, and other geometrical objects. This metaphysical conviction had two immediate consequences: that all the phenomena of nature can be in principle submitted to mathematics and that mathematical language is transparent; it is the language of nature itself and has simply to be picked up at the surface of phenomena. Finally, it goes without saying that, from a social point of view, the evolution of the sciences was apprehended through what has been aptly called the "relay runner model," according to which science progresses as a result of individual discoveries. Grand narratives such as this are perhaps simply fictions doomed to ruin as soon as they are clearly expressed. In any case, the very assumption on which this grand narrative relies can be brought into question: even in the canonical domain of mechanics, the relevant epistemological units crucial to understanding the dynamics of the Scientific Revolution are perhaps not a few laws of motion, but a complex set of problems embodied in mundane objects. Moreover, each of the theses just mentioned was actually challenged during the long period of historiographical reappraisal, out of which we have probably not yet stepped. Against the sharp distinction between a qualitative Aristotelian philosophy and the new quantitative physics, numerous studies insist that Rome wasn't built in a day, so to speak. Since Antiquity, there have always been mixed sciences; the emergence of pre-classical mechanics depends on both medieval treatises and the practical challenges met by Renaissance engineers. It is indeed true that, for Aristotle, mathematics merely captures the superficial properties of things, but the Aristotelianisms were many during the Renaissance and the Early Modern period, with some of them being compatible with the introduction of mathematics in natural philosophy. In addition, the gap between the alleged program of mathematizing nature and its effective realization was underlined as most natural phenomena actually escaped mathematization; at best they were enrolled in what Thomas Kuhn began to rehabilitate under the appellation of the "Baconian sciences," i.e., empirical investigations aiming at establishing isolated facts, without relating them to any overarching theory. Hence, mathematization of nature cannot pretend to capture a historical fact: at most, it expresses an indeterminate task for generations to come. On top of these first two considerations, and against the thesis of the neutrality of the mathematical language, it was urged that mathematics is not "only a language" and that, exactly as other symbolic means or cognitive tools, it has its own constraints. For example, it has been thoroughly explained that the Euclidean theory of proportions both guides and frustrates the Galilean analysis of motion; its shortages were particularly clear with respect to the expression of continuity, which is crucial in the case of motion. Consequently, when calculus was invented and applied to the analysis of motion, it was not a transposition that left things as they stood. Even more clearly than in the case of a translation from one natural language to another, the shift from one symbolic language to another entails that certain possibilities are opened while others are closed. The cognitive constraints imposed by established mathematical theories, as seen in the theory of proportions or calculus, were not the only ones to be studied in relation to mathematization. Certain schemes dependent on the grammar of natural languages, e.g., the scheme of contrariety, or certain symbolic means of representation, e.g. geometrical diagrams and numerical tables, were also subject to such scrutiny. Lastly, it was insisted that, even if we concede the existence of scientific geniuses, mathematics is largely produced by intellectual communities and embedded within social practices. More attention was consequently paid to the forms of communication in given mathematical networks, or to the teaching of the discipline in, for example, Jesuit colleges and universities. The set of mathematical practices specific to specialized craftsmen, highly-qualified experts and engineers began to be studied in its own right. All these reflections may have helped us change our perspectives on the question of mathematization. It seems, however, that they were instead set aside, both because of a general distrust towards sweeping narratives that are always subject to the suspicion that they overlook the unyielding complexity of real history, and because of a shift in our interests. The more obscure and idiosyncratic they are, an alchemist, a patron of the sciences or a lunatic collector is nowadays honored in journals of the history of sciences. As for the general issues involved in the question of mathematization, they are rejected as obsolete, or reserved for specialized journals in the history of mathematics. Consequently, before presenting the essays of this fascicle, I would like to say a few words in favor of a renewed study of the forms of mathematization in the history of the early sciences. (shrink)

Many views rely on the idea that it can never be rational to have high confidence in something like, “P, but my evidence doesn’t support P.” Call this idea the “Non-Akrasia Constraint”. Just as an akratic agent acts in a way she believes she ought not act, an epistemically akratic agent believes something that she believes is unsupported by her evidence. The Non-Akrasia Constraint says that ideally rational agents will never be epistemically akratic. In a number of recent papers, the (...) Non-Akrasia Constraint has been called into question. The goal of this paper is to defend it... for the most part. (shrink)

What determines qualitative sameness and difference? This book explores four principal accounts of the ontological basis of properties, including universals, trope theory, resemblance nominalism, and class nominalism, considering the assumptions and ontolological commitments which are required to make each into a plausible account of properties. -/- The latter half of the book investigates the applications of property theory and the different conceptions of properties which might be adopted with these in mind: first, the possibility and desirability of individuating properties, and (...) the distinction between sparse and abundant conceptions of properties; second, the distinction between intrinsic and extrinsic properties; third, the relationship between properties and their causal powers, and whether this is necessary or contingent; fourth, the relationship between properties and causation, modality, and laws of nature; finally, whether properties exist objectively, and if they do, what our epistemic position is with respect to such entities. (shrink)

What can Dungeons & Dragons teach us about the being of beings? This article argues that Dungeons & Dragons introduces us to a world composed of objects or entities, where the being of objects is defined not by their qualities, but rather by their powers, capacities or affects. Drawing on the thought of Spinoza, Deleuze and Molnar, objects are seen to be defined by what they can do or their capacities to act, such that qualities are effects of these acts. (...) Dungeons & Dragons is particularly suited to showing us this insofar as it focuses on the action of entities. (shrink)

We all experience loneliness at some time in our lives and it often motivates people, consciously or otherwise, to enter treatment. Yet it is rarely explicitly addressed in psychoanalytic literature. _Loneliness and Longing_ rectifies this oversight by thoroughly exploring this painful psychological state. In this book contributors address the inner sense of loneliness – that is feeling alone even in the company of others – by drawing on different aspects of loneliness and longing. Topics covered include: loneliness in the consulting (...) room the relationship between loneliness and love the effects of social networking and the internet how loneliness changes throughout the life-cycle healing the analyst’s loneliness. _Loneliness and Longing_ draws on both theory and practice to discuss ways to help people to understand and cope with this important emotional state, encouraging them to make loneliness and longing less pervasive in their lives. This will be ideal reading for analysts, psychotherapists, and related practitioners facing the challenges of loneliness in their consulting rooms. (shrink)